Search for Clinical Trial Results
Leber Congenital Amaurosis - 16 Studies Found
Status | Study |
Active, not recruiting |
Study Name: Safety Study in Subjects With Leber Congenital Amaurosis Condition: Leber Congenital Amaurosis Date: 2007-08-13 Interventions: Biological: AAV2-hRPE65v2 Subjects will be dosed unilaterally (one eye) beginning with the lowest dose. |
Completed |
Study Name: Genetic Decryption of Leber Congenital Amaurosis (LCA) in a Large Cohort of Independent Families. Condition: Leber Congenital Amaurosis Date: 2016-11-17 |
Active, not recruiting |
Study Name: Phase 1/2 Safety and Efficacy Study of AAV-RPE65 Vector to Treat Leber Congenital Amaurosis Condition: Leber Congenital Amaurosis Date: 2008-09-08 Interventions: Biological: rAAV2-CB-hRPE65 Recombinant adeno-associated virus vector expressing RPE65 |
Not yet recruiting |
Study Name: Study to Evaluate QR-110 in Subjects With Leber's Congenital Amaurosis (LCA) Due to the c.2991+1655A>G Mutation (p.Cys998X) in the CEP290 Gene Condition: Leber's Congenital Amaurosis Date: 2017-05-01 Interventions: Drug: QR-110 RNA antisense oligonucleotide for intravitreal injection |
Recruiting |
Study Name: Natural History Study of Patients With Leber Congenital Amaurosis Associated With Mutations in RPE65 Condition: Leber Congenital Amaurosis Date: 2016-03-08 |
Active, not recruiting |
Study Name: Phase 1 Follow-on Study of AAV2-hRPE65v2 Vector in Subjects With Leber Congenital Amaurosis (LCA) 2 Condition: Leber Congenital Amaurosis Date: 2010-09-22 Interventions: Biological: AAV2-hRPE65v2 One time, subretinal administration of 1.5E11 vg AAV2-hRPE65v2 vector to the c |
Active, not recruiting |
Study Name: Safety and Efficacy Study in Subjects With Leber Congenital Amaurosis Condition:
|
Recruiting |
Study Name: Clinical Trial of Gene Therapy for the Treatment of Leber Congenital Amaurosis (LCA) Condition: Leber Congenital Amaurosis Date: 2016-04-28 Interventions: Genetic: AAV2/5 OPTIRPE65 |
Recruiting |
Study Name: Clinical Trial of Gene Therapy for Leber Congenital Amaurosis Caused by RPE65 Mutations Condition: Leber Congenital Amaurosis Date: 2009-01-12 Interventions: Genetic: rAAV2-hRPE65 Uniocular subretinal injections; relative doses: Cohort 1 - basic (lowest) viral d |
Completed |
Study Name: Repeated Treatments of QLT091001 in Subjects With Leber Congenital Amaurosis or Retinitis Pigmentosa (Extension of Study RET IRD 01) Condition:
Date: 2012-01-06 Interventions: Drug: QLT091001 oral QLT091001 administered once daily for 7 days |