Congestive cardiomyopathy, or heart failure, is a disease that affects the heart's ability to pump blood throughout the body. It can be caused by high blood pressure, coronary artery disease, excessive alcohol consumption and other factors. Familial congestive cardiomyopathy (FCM) is a rare genetic disorder that causes symptoms similar to heart failure.
- FCM occurs when there is a defect in one of the genes responsible for producing proteins needed to build muscle cells. This defect causes the muscle fibers in your heart to become weak, which prevents them from contracting normally and pumping blood throughout your body. Over time, this weakness leads to reduced cardiac output and other symptoms associated with congestive cardiomyopathy.
- The exact cause of FCM is unknown; however, it runs in families and can be inherited from parents who have it themselves or pass on a defective gene to their children through either autosomal dominant inheritance (the child gets one copy of a mutated gene from each parent) or autosomal recessive inheritance (both parents must pass along a copy of a mutated gene).
- The most common symptom of FCC is shortness of breath during physical activity.
- The condition can also cause swelling in the legs and abdomen due to fluid build-up around the lungs (pulmonary edema).
Shortness of breath,Fatigue,Swelling in the legs, ankles, feet, or abdomen,Feeling faint or dizzy,Chest pain
Diabetes,High blood pressure,Anxiety disorder or stress,Alcoholism,Obesity
Sacubitril/valsartan (Entresto),Water pills (diuretics),Digoxin (Lanoxin),Ivabradine (Corlanor),Blood-thinners (anticoagulants)