There is no cure for takayasu disease (takayasu arteritis). However, a comprehensive treatment plan can be followed to improve the symptoms, reduce inflammation and prevent irreversible damage to artery walls. Takayasu disease or Takayasu Arteritis (TAK) is a type of vasculitis, a rare familial disorder characterized by inflammation of blood vessels. The condition affects the aorta and its branches, which resist the flow of blood, eventually damaging the vital organs and tissues.
Early detection and proper treatment will decrease the risk of severe complications, including,
- Corticosteroids – This is the initial treatment plan that involves the utilization of steroids, including prednisone, which is prescribed at a high dosage in the first stage. After a certain period, the dosage will be reduced, in response to minimizing side effects.
- Immunosuppressants – Medications such as methotrexate or azathioprine are used to suppress the action of the immune system and reduce the need for prednisone.
- Biologics – Biologics are complex proteins produced from living organisms that are used to control inflammation and lower the need for steroid medications. However, the treatment still needs more scientific evidence.
- Surgery – Vascular surgery will be suggested in some cases, when the arteries are potentially damaged or narrowed, or to resolve aneurysms.
Pain or weakness in limbs,Dizziness,Deadaches,Visual disturbances,High Blood Pressure,Diminished pulse,Anemia,Chest pain,Shortness of breath, Fatigue,Sudden weight loss,Troubled concentration
Hardening and narrowing of blood vessels,Aortic Valve damage,Heart failure,Aortic Aneurysm,Transient Ischemic Attack (Mini-stroke that can cause permanent damage),Heart attack,Pulmonary artery problems
Corticosteroids (Prednisone),Cytotoxic drugs (Methotrexate, Azathioprine),Biologics (Infliximab, Rituximab)